Endocrine Abstracts

The pre-diabetic autoimmune process leading to clinical type 1 diabetes may start already during early infancy. As the incidence of type 1 diabetes is increasing most rapidly among children younger than 5 years in many high and middle income countries (Patterson et al. 2009), there is increasing interest in the impact of early exposures such as diet even before birth.Vitamin D has several effects on the immune system, which could be of potential r...

The rapidly increasing incidence of T1D worldwide and studies among migrants have shown that environmental factors play an important role in the pathogenesis of T1D. Identification of these risk-modulating factors would offer an excellent opportunity to develop effective strategies for prevention of T1D. Vitamin D is one of the main candidates for protection from type 1 diabetes, although prospective epidemiological studies on the effect of vitamin D exposure during pregnancy,...